Chloroma

Chloromas are rare; exact estimates of their prevalence are lacking, but they are uncommonly seen even by physicians specializing in the treatment of leukemia. Chloromas may be somewhat more common in patients with the following disease features:

⇒ French-American-British (FAB) classification class M2

⇒ WHO Classification (2016 revision) is a separate entity under the “Acute myeloid leukemia (AML) and related neoplasms”

⇒ those with specific cytogenetic abnormalities (e.g. t(8;21) or inv(16))

⇒ those whose myeloblasts express T-cell surface markers, CD13, or CD14

⇒ those with high peripheral white blood cell counts